Microfluidic devices can manipulate small volumes of fluids with high precision which has enabled innovations in point-of-care testing, organ-on-a-chip models, and high-throughput screening. With growing demand for scalable, cost-effective platforms, the industry is rapidly shifting toward thermoplastic-based microfluidic devices, especially those made from cyclic olefin copolymers (COC). Injection molding combined with thermal diffusion bonding has…